PL05.04: Translational Lung Cancer Research
نویسندگان
چکیده
منابع مشابه
Small-cell lung cancer: translational research enroute to therapeutic advances.
Hann and Rudin have provided a comprehensive and thoughtful review of the current management of small-cell lung cancer (SCLC). As they note, for approaching 2 decades, little has changed in the pretreatment evaluation, staging, or treatment of this disease. As a result, only modest improvements in survival have been seen. During this time, however, a considerable understanding of the biology of...
متن کاملKey genes in lung cancer translational research: a meta-analysis.
In lung cancer, integrating translational data from various histologies obtained in different patients under different conditions can increase their robustness. This is a meta-analysis of cDNA array data obtained in 688 tumor patients (541 non-small cell lung cancer, 33 small cell lung cancer and 114 others) and 205 controls. 1,206 genes were found to be dysregulated in one of the 12 transcript...
متن کاملSmall-Cell Lung Cancer: Translational Research Enroute to Therapeutic Advances
Hann and Rudin have provided a comprehensive and thoughtful review of the current management of small-cell lung cancer (SCLC). As they note, for approaching 2 decades, little has changed in the pretreatment evaluation, staging, or treatment of this disease. As a result, only modest improvements in survival have been seen. During this time, however, a considerable understanding of the biology of...
متن کاملTranslational Cancer Research Program
Tumor microenvironment regulates cancer cell survival, metastasis, inflammation, and immune surveillance. There is growing evidence that the lymph node (LN) microenvironment, especially lymph node stromal cells (LNSCs), play a significant role in solid tumor growth, drug resistance, and subsequent extra-nodal metastasis of many types of cancer. A comprehensive understanding of the associated mo...
متن کاملTranslational research in breast cancer.
Translational research (TR) involves both the development of novel diagnostics and novel therapeutics. These two major developmental areas are often associated with each other and these associations often bring new paradigms in the management of cancer patients. For example, the development of trastuzumab-based treatments has been conducted in harmony with the development of new methodologies t...
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ژورنال
عنوان ژورنال: Journal of Thoracic Oncology
سال: 2017
ISSN: 1556-0864
DOI: 10.1016/j.jtho.2016.11.017